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| Name | Class |
|---|---|
| Guangdong Provincial People's Hospital | OTHER |
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Antiplatelet therapy is the cornerstone for the prevention of atherothrombosis in patients with coronary artery disease (CAD). However, the efficacy and safety of antiplatelet therapy are varied due to ethnic and/or individual variability. The aim of the OPT-CAD study was to demonstrate contemporary status and outcomes of antiplatelet therapy in Chinese CAD patients, and to explore predictors of ischemic or bleeding events in such cohort.Patients above 18 years old who were diagnosed as CAD and received antiplatelet therapy were prospectively enrolled in this national wide, non-intervention registry. All medications and laboratory tests were physician discretion.
Antiplatelet therapy is the cornerstone for the prevention of atherothrombosis in patients with coronary artery disease (CAD). However, the efficacy and safety of antiplatelet therapy are varied due to ethnic and/or individual variability. The aim of the OPT-CAD study was to demonstrate contemporary status and outcomes of antiplatelet therapy in Chinese CAD patients, and to explore predictors of ischemic or bleeding events in such cohort.Patients above 18 years who were diagnosed as CAD and received antiplatelet therapy were prospectively enrolled in this national wide, non-intervention registry. All medications and laboratory tests were at physician discretion.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Antiplatelet therapy | patients with coronary artery disease receiving any antiplatelet therapy, without any intervention by the investigators. |
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| Measure | Description | Time Frame |
|---|---|---|
| Major adverse cardiac and cerebral events | a composite of all cause death, myocardial infarction, stroke or any revascularization or stroke | 12month |
| Measure | Description | Time Frame |
|---|---|---|
| all cause death | 12month | |
| Stent thrombosis | by BARC definition | 12 month |
| rehospitalization |
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Inclusion criteria:
Exclusion Criteria:
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Patient of coronary heart disease receiving any antiplatelet therapy
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| Name | Affiliation | Role |
|---|---|---|
| Yaling Han, MD | Shenyang Military Region General Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The first affiliated hospital of Bengbu Medical College | Bengbu | Anhui | China | |||
| Beijing Anzhen Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32418142 | Derived | Ma S, Jiang Z, Qiu M, Li Z, Bian L, Li Y, Han Y. Dual Antiplatelet Therapy Duration in Medically Managed Acute Coronary Syndrome Patients: Sub-Analysis of the OPT-CAD Study. Adv Ther. 2020 Jul;37(7):3150-3161. doi: 10.1007/s12325-020-01376-0. Epub 2020 May 16. | |
| 30334527 | Derived | Feng YQ, He XY, Song FE, Chen JY. Association between Contrast Media Volume and 1-Year Clinical Outcomes in Patients Undergoing Coronary Angiography. Chin Med J (Engl). 2018 Oct 20;131(20):2424-2432. doi: 10.4103/0366-6999.243563. |
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any rehospitalization for cardiac or noncardiac reasons |
| 12 month |
| any bleeding events | by BARC definition | 12 month |
| recurrent angina | 12 month |
| myocardial infarction | 12 months |
| stroke | 12 months |
| any revascularization | 12 months |
| Beijing |
| Beijing Municipality |
| China |
| Navy General Hospital | Beijing | Beijing Municipality | China |
| The 304th Hospital of PLA | Beijing | Beijing Municipality | China |
| The 306th of PLA | Beijing | Beijing Municipality | China |
| The Luhe teaching hospital of the Capital Medical University | Beijing | Beijing Municipality | China |
| The People's Hospital of Beijing University | Beijing | Beijing Municipality | China |
| Yanshan hospital | Beijing | Beijing Municipality | China |
| Beijing Fuwai Hospital | Beijin | Beijing Municipality | China |
| Third Military Medical University Xinqiao Hospital | Chongqing | Chongqing Municipality | China |
| The 174th Hospital of PLA | Xiamen | Fujian | China |
| Lanzhou military region general hospital | Lanzhou | Gansu | China |
| The First Affiliated Hospital of Guangzhou Medical College | Guangdong | Guangdong | China |
| General hospital of armed police foreces in Guangzhou | Guangzhou | Guangdong | China |
| Guangdong General Hospital | Guangzhou | Guangdong | China |
| Guangzhou Baiyun district hospital | Guangzhou | Guangdong | China |
| Guangzhou military region general hospital | Guangzhou | Guangdong | China |
| Guangzhou Panyu district central hospital | Guangzhou | Guangdong | China |
| Liwan District People's Hospital of Guangzhou | Guangzhou | Guangdong | China |
| The first hospital of Guangzhou | Guangzhou | Guangdong | China |
| Shenzhen Longgang center hospital | Shenzhen | Guangdong | China |
| Zhuhai people's hospital | Zhuhai | Guangdong | China |
| The 3rd people's hospital of Nanning | Nanning | Guangxi | China |
| Guizhou provincial people's hospital | Guiyang | Guizhou | China |
| The 425th of PLA | Sanya | Hainan | China |
| Affiliated hospital of Hebei University of Engineering | Handan | Hebei | China |
| The People's Hospital of Tangxian | Renhou | Hebei | China |
| The people's hospital of Rongcheng | Rongcheng | Hebei | China |
| Bethune International Peace Hospital | Shijiazhuang | Hebei | China |
| The 251st of PLA | Zhangjiakou | Hebei | China |
| Daqing oil field hospital | Daqing | Heilongjiang | China |
| Heilongjiang provincial hospital | Harbin | Heilongjiang | China |
| The 211st of PLA | Harbin | Heilongjiang | China |
| The third affiliated hospital of Qiqihar Medical University | Qiqihar | Heilongjiang | China |
| The People's Hospital of Hebi | Hebi | Henan | China |
| The 152nd Hospital of PLA | Pingdingshan | Henan | China |
| The People's Hospital of Zhecheng County | Zhecheng Chengguanzhen | Henan | China |
| The First Hospital of Organization Directly Under Henan Province | Zhengzhou | Henan | China |
| Wuhan Asia heart hospital | Wuhan | Hubei | China |
| The first hospital of Changshan | Changshan | Hunan | China |
| The general hospital of Xilingol League | Mositai | Inner Mongolia | China |
| The first hospital of Nanjing | Nanjing | Jiangsu | China |
| The central hospital of Nantong | Nantong | Jiangsu | China |
| The Affiliated Hospital of Jinggangshan University | Ji’an | Jiangxi | China |
| Central Hospital of Changchun | Changchun | Jilin | China |
| The affiliated hospital to Changchun University of Chinese Medicine | Changchun | Jilin | China |
| The China-Japan union hospital of Jilin University | Changchun | Jilin | China |
| The First Affiliated Hospital of Jilin University | Changchun | Jilin | China |
| The Second Affiliated Hospital of Jilin University | Changchun | Jilin | China |
| The 222nd of PLA | Jilin City | Jilin | China |
| Meihekou central hospital | Meihekou | Jilin | China |
| Siping first people's hospital | Siping | Jilin | China |
| The 206th of PLA | Tonghua | Jilin | China |
| The people's hospital of Tonghua | Tonghua | Jilin | China |
| Tonghua central hospital | Tonghua | Jilin | China |
| Anshan central hospital | Anshan | Liaoning | China |
| Anshan hospital affiliated of China Medical University | Anshan | Liaoning | China |
| The first affiliated hospital of Liaoning Medical University | Anshan | Liaoning | China |
| The people's hospital of Xiuyan | Anshan | Liaoning | China |
| The third hospital of Anshan | Anshan | Liaoning | China |
| Dalian municipal central hospital affiliated of Dalian Medical University | Dalian | Liaoning | China |
| The 210th Hospital of PLA | Dalian | Liaoning | China |
| Zhongshan Hospital Affiliated to Dalian University | Dalian | Liaoning | China |
| The 230th of PLA | Dandong | Liaoning | China |
| The people's hospital of Dandong | Dandong | Liaoning | China |
| Central Hospital affiliated to Shenyang Medical College | Fengtian | Liaoning | China |
| Fushun central hospital | Fushun | Liaoning | China |
| The 7th hospital of China Medical University | Fushun | Liaoning | China |
| The Second Affiliated and gynecology and obstetirs hospital of Fuxin city | Fuxin | Liaoning | China |
| The people's hospital of Haicheng | Haicheng | Liaoning | China |
| The 205th of PLA | Jinzhou | Liaoning | China |
| The third affiliated hospital of Liaoning medical College | Jinzhou | Liaoning | China |
| Central hospital of Liaoyang | Liaoyang | Liaoning | China |
| Liaoyang Chemical General Hospital | Liaoyang | Liaoning | China |
| The 201th Hospital of PLA | Liaoyang | Liaoning | China |
| The 2nd people's hospital of Liaoyang | Liaoyang | Liaoning | China |
| Jinqiu Hospital | Shenyang | Liaoning | China |
| Liaoning northern hospital | Shenyang | Liaoning | China |
| Shenyang the forth hospital of people | Shenyang | Liaoning | China |
| The 202nd Hospital of PLA | Shenyang | Liaoning | China |
| The 242nd of PLA | Shenyang | Liaoning | China |
| The 245th of PLA | Shenyang | Liaoning | China |
| The 463rd Hospital of PLA | Shenyang | Liaoning | China |
| The First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine | Shenyang | Liaoning | China |
| The first people's hospital of Shenyang | Shenyang | Liaoning | China |
| The Forth affiliated hospital of Liaoning University of Traditional Chinese Medicine | Shenyang | Liaoning | China |
| The Second Affiliated Hospital of Shenyang Medical College | Shenyang | Liaoning | China |
| The Third Affiliated Hospital of Shenyang Medical College | Shenyang | Liaoning | China |
| Traditional Chinese Medicine hospital of Shenyang | Shenyang | Liaoning | China |
| Yingkou Development Zone Hospital | Yingkou | Liaoning | China |
| General hospital of Ningxia Medical University | Yinchuan | Ningxia | China |
| The people's hospital of Huzhu | Huzhu | Qinghai | China |
| Tangdu hospital | Xi'an | Shaanxi | China |
| Jinan military general hospital | Jinan | Shandong | China |
| Jiaozhou central hospital | Qingdao | Shandong | China |
| Wanjie Hospital | Zibo | Shandong | China |
| Eastern hospital in Shanghai | Shanghai | Shanghai Municipality | China |
| Yuncheng central hospital | Yuncheng | Shanxi | China |
| Sichuan military general hospital | Chengdu | Sichuan | China |
| Armed police foreces'hospital of Tianjin | Tianjin | Tianjin Municipality | China |
| The 254th of PLA | Tianjin | Tianjin Municipality | China |
| Xizang military general hospital | Lhasa | Tibet | China |
| The 11st of PLA | Huiyuan | Xinjiang | China |
| General hospital of Wulumuqi | Ürümqi | Xinjiang | China |
| The Chest Hospital of Xinjiang Uyghur Autonomous Region | Ürümqi | Xinjiang | China |
| The 4th public hospital of Honghe | Yisa | Yunnan | China |
| Hangzhou first people's hospital | Hangzhou | Zhejiang | China |
| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
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