This research is being done to look at the association between migraine and obesity.

Research into the role of inflammatory markers and other obesity related proteins and chemicals may help us understand migraine and lead to new treatment.

Inclusion Criteria:

• Premenopausal women (18-55 years)
• Normal weight (BMI = 18.5 - 24.9) or obese (BMI ≥ 30)
• Diagnosis of episodic or chronic migraine or pain free control

Exclusion Criteria:

• Evidence of pain disorder other than migraine (e.g. irritable bowel syndrome)
• Chronic conditions known to alter risk or pattern of migraine (e.g. hypothyroidism)
• Illnesses that may affect adipokine levels (e.g. diabetes)
• Clinically relevant abnormal glucose/cholesterol levels
• Pregnant women
• Potential participants who are unable to undergo MRI based on standard screening questionnaire (those with brain aneurysm or surgical clips, certain types of artificial heart valves, heart defibrillator or pacemaker, cochlear implants, eye implants, blood vessel coil, recently placed artificial joints, certain types of vascular stents, history of bullets, pellets, BBs, history of any implanted metal or device or who have worked with sheet metal in the past)

Premenopausal Caucasian women ages 18-55 years with or without migraine.