The Identification and Characterization of Autonomic Dysfunction in Migraineurs With and Without Auras

The Identification and Characterization of Autonomic Dysfunction in Migraineurs With and Without Auras

This is a study to compare subject response and symptoms resulting from administration of three clinical assessments.

* The 3 assessments are

1. passive upright tilt table testing,
2. quantitative sudomotor axon reflex testing (QSART)and
3. punch biopsy.

The comparison of results will be from two subject groups:

• Group A, the migraine suffering patient with or without aura
• Group B, the migraine suffering patient with or without aura who has diagnosed orthostatic intolerance (i.e.,feeling dizzy or faint when making a body position change).

Inclusion Criteria:

• age 18 to 65
• male or female
• migraine diagnosis
• may or may not have orthostatic intolerance
• able to demonstrate study understanding and complete informed consent process

Exclusion Criteria:

• subjects who do not meet inclusion criteria
• subjects unable to complete informed consent process