Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Studies have shown that an acute bout of aerobic exercise positively effects cognition, mainly executive functioning; however the effect is not observed among all people and it is not clear whether only aerobic exercise can produce this effect or possibly also resistant exercise. The main purpose of our study is to examine whether genetic variation is a moderator of this effect and whether resistant exercise is comparable to aerobic exercise in improving cognition following a single bout of exercise.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Exercise Group | Experimental | Each individual subject will give a blood sample for genetic analysis and undertake an exercise session and a rest session as a control. Cognitive function will be tested before and after each session. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cognitive function after exercise test | Other | The individual subjects will participate in 3 sessions of either aerobic exercise, resistance exercise or rest, in a random order. Before and after each session, the subject will take computerized cognitive tests. |
| Measure | Description | Time Frame |
|---|---|---|
| Cognitive Functioning After Exercise | Computerized battery of tests evaluating cognitive functioning | Five minutes |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Genetic Variation Associated with Different Cognitive Functioning | Genetic variation will be analyzed by extraction of genomic DNA from blood leukocytes, using a salting out procedure, and then by using polymerase chain reaction restriction fragment lengths polymorphism (PCR-RELP) methods for detection of single nucleotide polymorphism. A mutation will be discriminated by digestion with specific restriction endonucleases. |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sharon Tsuk, PhD | Contact | 972-522-640642 | sharontsuk1@gmail.com |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Wingate Institute | Netanya | Israel |
|
Not provided
Not provided
Not provided
Not provided
| Blood sample analysis | Genetic | In the first evaluation session blood samples will be taken from each subject and will be analysed for genetic polymorphism. |
|
| Two years |