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The purpose of this study is to compare the impact of high- and low-intensity resistance exercise on force-velocity characteristics, muscle mass and inflammatory processes in older adults. As all training protocols are designed to end with maximal effort, effects are expected to be similar between groups.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High-load strength training | Active Comparator |
| |
| Low-load strength training | Active Comparator |
| |
| Low-load + moderate-load strength training | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Strength training | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in force-velocity characteristics of knee extensors | Baseline, 12weeks, 6 months |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in muscle volume | Baseline, 12weeks, 6 months | |
| Change in maximal strength (one repetition maximum) | Strength is measured as the maximum weight on the training equipment that can be lifted only one time (= one repetition maximum). |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Kinesiology and Rehabilitation Sciences | Leuven | Leuven | 3001 | Belgium |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28778747 | Derived | Van Roie E, Walker S, Van Driessche S, Baggen R, Coudyzer W, Bautmans I, Delecluse C. Training load does not affect detraining's effect on muscle volume, muscle strength and functional capacity among older adults. Exp Gerontol. 2017 Nov;98:30-37. doi: 10.1016/j.exger.2017.07.017. Epub 2017 Aug 1. | |
| 28244559 | Derived |
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| ID | Term |
|---|---|
| D055070 | Resistance Training |
| ID | Term |
|---|---|
| D005081 | Exercise Therapy |
| D012046 | Rehabilitation |
| D000359 | Aftercare |
| D003266 | Continuity of Patient Care |
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| Baseline, 4weeks, 8weeks, 12weeks, 6 months |
| Change in motivation | Baseline, every week for 12 weeks, 6 months |
| Change in physical activity | Baseline, 12weeks, 6 months |
| Change in inflammatory markers in blood | Baseline, 12weeks, 6 months |
| Nuvagah Forti L, Van Roie E, Njemini R, Coudyzer W, Beyer I, Delecluse C, Bautmans I. High Versus Low Load Resistance Training: The Effect of 24 Weeks Detraining on Serum Brain Derived-Neurotrophic Factor (BDNF) in Older Adults. J Frailty Aging. 2017;6(1):53-58. doi: 10.14283/jfa.2017.2. |
| D005791 |
| Patient Care |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D064797 | Physical Conditioning, Human |
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |