Induction and maintaining of anaesthesia with Propofol. Analgesia either with Fentanyl or Fentanyl+Remifentanyl.

Cisatracurium (Nimbex):

• initial dose: 0.2 mg/kg
• maintaining dose: 0.1 mg/kg (repeated anytime TOF-count reaches 2 twitches)

At the end of the surgical operation, patients will be administered Neostigmine 0.04 mg/kg and Atropine 0.02 mg/kg.

Patients will be extubated with a TOF-Ratio of at least 0.90.

Induction and maintaining of anaesthesia with Propofol. Analgesia either with Fentanyl or Fentanyl+Remifentanyl

Rocuronium (Esmeron):

• initial dose: 0.6 mg/kg
• maintaining dose: 0.15 mg/kg (repeated anytime TOF-count reaches 2 twitches)

At the end of the surgical operation, patients will be administered Neostigmine 0.04 mg/kg and Atropine 0.02 mg/kg.

Patients will be extubated with a TOF-Ratio of at least 0.90.

Cisatracurium (Nimbex):

• initial dose: 0.2 mg/kg
• maintaining dose: 0.1 mg/kg (repeated anytime TOF-count reaches 2 twitches)

To determine the incidence of post-operative residual curarization in our operating rooms, comparing two different neuromuscular-blocking agents: Cisatracurium and Rocuronium.

The primary endpoint is quantified with TOF-Ratio, determined with the device TOF-Watch SX (Organon, Netherlands). A TOF-Ratio<0.90 defines PORC.

Three clinical parameters (head-tilt for 5 seconds, ability to swallow, presence of diplopia) are also evaluated.

TOF-Ratios, as long as the above-mentioned clinical parameters are determined and evaluated at 15, 30 and 60 minutes after extubation of the patient.