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Preoperative use of finastride will decrease the amount of perioperative blood loss during and after TURP
The effect of finastride on decreasing the amount of perioperative blood loss during and after TURP is dose dependent
Finastride will decrease microvascular density in prostate tissue and this effect is dose dependent
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Finastide low dose | Active Comparator | 2 weeks of daily 5mg finastride before operation |
|
| Finastide high dose | Active Comparator | 4 weeks of daily 5mg finastride before operation |
|
| Control | No Intervention | Control |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| TURP | Procedure | Transurthral resection of prostate |
|
| Measure | Description | Time Frame |
|---|---|---|
| Perioperative Hb Drop | 24 hours after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faghihi Hospital | Shiraz | Fars | 71344 | Iran |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26945662 | Derived | Aminsharifi A, Salehi A, Noorafshan A, Aminsharifi A, Alnajar K. Effect of Preoperative Finasteride on the Volume or Length Density of Prostate Vessels, Intraoperative, Postoperative Blood Loss during and after Monopolar Transurethral Resection of Prostate: A Dose Escalation Randomized Clinical Trial Using Stereolog Methods. Urol J. 2016 Mar 5;13(1):2562-8. |
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| ID | Term |
|---|---|
| D011470 | Prostatic Hyperplasia |
| ID | Term |
|---|---|
| D011469 | Prostatic Diseases |
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
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| ID | Term |
|---|---|
| D020728 | Transurethral Resection of Prostate |
| ID | Term |
|---|---|
| D011468 | Prostatectomy |
| D013521 | Urologic Surgical Procedures, Male |
| D013520 | Urologic Surgical Procedures |
| D013519 | Urogenital Surgical Procedures |
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| D052801 |
| Male Urogenital Diseases |
| D013514 | Surgical Procedures, Operative |