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Anesthesia induction with sevoflurane is not associated with an increased incidence or severity of laryngeal injuries compared with an anesthesia induction with a muscle relaxant.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| sevoflurane | Active Comparator | anesthesia induction with propofol, remifentanil and sevoflurane |
|
| rocuronium | Active Comparator | anesthesia induction with propofol, remifentanil and rocuronium |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sevoflurane | Drug | anesthesia induction with propofol, remifentanil and sevoflurane; afterwards tracheal intubation |
|
| Measure | Description | Time Frame |
|---|---|---|
| incidence of vocal cord injuries | 24 h after tracheal intubation |
| Measure | Description | Time Frame |
|---|---|---|
| incidence of hoarseness | 24h, 48 h, and 72 h after tracheal intubation | |
| incidence of soar throat | 24h, 48h, and 72 h after tracheal intubation |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Rostock | Rostock | Mecklenburg-Vorpommern | 18057 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24860256 | Derived | Mencke T, Jacobs RM, Machmueller S, Sauer M, Heidecke C, Kallert A, Pau HW, Noeldge-Schomburg G, Ovari A. Intubating conditions and side effects of propofol, remifentanil and sevoflurane compared with propofol, remifentanil and rocuronium: a randomised, prospective, clinical trial. BMC Anesthesiol. 2014 May 22;14:39. doi: 10.1186/1471-2253-14-39. eCollection 2014. |
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| ID | Term |
|---|---|
| D006685 | Hoarseness |
| D010612 | Pharyngitis |
| ID | Term |
|---|---|
| D014832 | Voice Disorders |
| D007818 | Laryngeal Diseases |
| D012140 | Respiratory Tract Diseases |
| D012120 | Respiration Disorders |
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| ID | Term |
|---|---|
| D000077149 | Sevoflurane |
| D000077123 | Rocuronium |
| ID | Term |
|---|---|
| D008738 | Methyl Ethers |
| D004987 | Ethers |
| D009930 | Organic Chemicals |
| D006845 | Hydrocarbons, Fluorinated |
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| Rocuronium | Drug | anesthesia induction with propofol, remifentanil and rocuronium; afterwards tracheal intubation |
|
| D010038 |
| Otorhinolaryngologic Diseases |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012818 | Signs and Symptoms, Respiratory |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D010608 | Pharyngeal Diseases |
| D009057 | Stomatognathic Diseases |
| D006846 |
| Hydrocarbons, Halogenated |
| D006838 | Hydrocarbons |
| D000732 | Androstanols |
| D000731 | Androstanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |