Postprandial Insulin Secretion, Oxidative Stress and Gastrointestinal Peptides in Patients With Type 2 Diabetes Versus Healthy Subjects

Insulin secretion, plasma lipids, oxidative stress markers and gastrointestinal peptides will be measured in patients with type 2 diabetes versus healthy subjects in a fasting status and in response to standard meals (at times 0', 30', 60', 120' and 180').

Inclusion Criteria:

• 40 individuals with type 2 diabetes treated by diet only or oral hypogylycemic agents,
• diabetes duration at least 1 year,
• both men and women,
• age 30-65 years,
• BMI 27-50 kg/m². The subjects will be explained aims, methods and risks of the study and they will sign informed consent

Exclusion Criteria:

• gravidity,
• lactation,
• drug abuse,
• insulin therapy