Postoperative Desogestrel for Endometriosis Related Pain

A Prospective Double Blind Randomized Controlled Trial to Study the Effectiveness of a Desogestrel for the Treatment of Pelvic Pain or Dysmenorrhea in the Patients Undergone Conservative Surgery for Pelvic Endometriosis

Endometriosis is one of the most common disease in reproductive aged women.Surgical intervention has a significant symptoms relief. However, symptom recurrence is often after surgery. This study aims to determine the efficacy of Desogestrel compared with placebo in pain symptom of symptomatic endometriosis patient undergo conservative surgery . The primary outcome measurement is pain score at 6 months after surgery.

After conservative surgery, the patients are randomized to Desogestrel and placebo groups. VAS pain score are compared after complete 6 months

Inclusion Criteria:

• diagnoses endometriosis
• Plan conservative surgery
• initial pain score at least 5
• voluntary to be the participant of this study with inform consent
• No desired child bearing in 6 months

Exclusion Criteria:

• residual lesion after surgery which required further treatment
• cannot participate complete 6 months after surgery
• contraindication for Desogestrel, Paracetamol or Ponstan
• Pregnant