Changes of Endothelial Function Before and After DSA in Patients With Diabetes

Changes of Endothelial Function Before and After DSA in Patients With Diabetes

Endothelial dysfunction is the early step of atherosclerosis. Therefore, the investigators hypothesize that digital subtraction angiography (DSA) can damage endothelial function. In this study, the investigators will select 200 diabetic patients who have a DSA for diabetic foot screening. Also, the investigators will select 100 healthy subjects as controls. The endothelial function will be determined by high resolution ultrasound before and after DSA. The investigators will observe the changes of endothelial function after DSA assay.

Inclusion Criteria:

• Patients with diabetic foot
• Age 40 to 70 years old

Exclusion Criteria:

• Heart failure
• Renal failure
• Acute infection