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unable to enrollment subjects due to early departure of study personele
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The investigators hypothesize that continuously measuring stroke volume (SV) and cardiac output (CO) will 1) reveal hemodynamic instability in a timely manner and alert the physician promptly, 2) provide information for the physician to make the differential diagnosis as to whether the hemodynamic instability was due to vasodilatation or reduction of venous blood return, and 3) lead to appropriate and prompt treatment to improve patient outcome.
-determine the SV and CO and their kinetic change using ICONĀ® to establish a hemodynamic profile of the patient under spinal anesthesia for cesarean section. To determine if using instantaneous measurements of SV and CO to guide patient management improves hemodynamic stability.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Other | The patients in Group A will serve as controls and will receive standard monitoring in addition to continuous measurement of SV and CO. The physicians will not know the CO and SV and will manage the patients in a standard fashion. |
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| experimental | Experimental | The patients in Group B will receive the same monitoring as those in Group A. But the physicians will know instantaneously the CO and SV in real time and will manage the patients accordingly. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| experimental | Procedure | Non-invasive cardiac output monitoring using thoracic electric bioimpedance analysis via ICONĀ® in addition of the standard monitoring during cesarean section. |
| Measure | Description | Time Frame |
|---|---|---|
| Maximum percentage changes in mean blood pressure after spinal anesthesia | baseline before spinal anesthesia and up to 20 minutes after spinal anesthesia |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yandong Jiang, MD, PhD | Massachusetts General Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States |
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| Control | Procedure | Data obtained from the non-invasive cardiac output monitor,ICONĀ®, are not available for the anesthesia care providers. |
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