How Fat Influences the Brain | NCT01516021 | Trialant

How Fat Influences the Brain | NCT01516021 | Trialant

Sponsor/Collaborators Module

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
high fat yoghurt intake	Experimental	500 ml of a high fat yoghurt	Dietary Supplement: intake of high or low fat yoghurt
low fat yoghurt intake	Experimental		Dietary Supplement: intake of high or low fat yoghurt

Interventions

Name	Type	Description	Arm Group Labels	Other Names
intake of high or low fat yoghurt	Dietary Supplement	intake of 500 ml of a high fat yoghurt on one day and intake of 500 ml of a low fat yoghurt on the other day	high fat yoghurt intake

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Changes in Cerebral Blood Flow due to the high or low fat yoghurt intake after 30 minutes and 120 minutes compared to a baseline measurement 30 minutes before yoghurt intake.	We were interested in differential brain activations due to the high or low fat meal. To assess this, the mentioned time points are suitable. The Cerebral Blood Flow is measured using Arterial Spin Labeling sequences in a functional magnetic resonance tomography.	30 minutes before as well as 30 minutes and 120 minutes after fat intake

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
22572644	Derived	Frank S, Linder K, Kullmann S, Heni M, Ketterer C, Cavusoglu M, Krzeminski A, Fritsche A, Haring HU, Preissl H, Hinrichs J, Veit R. Fat intake modulates cerebral blood flow in homeostatic and gustatory brain areas in humans. Am J Clin Nutr. 2012 Jun;95(6):1342-9. doi: 10.3945/ajcn.111.031492. Epub 2012 May 9.