Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Perturbations in microRNA (miRNA) expression profiles has been reported for a variety of cancers. This study will be an exploratory analysis of miRNA expression in basal cell carcinoma by miRNA expression profiling using microarrays.
Perturbations in the expression profiles of microRNAs (miRNAs) have been reported for a variety of different cancers. Basal cell carcinoma (BCC) of the skin has not been systematically evaluated regarding differentially expressed miRNAs. Patients with BCC are included in the study to perform an exploratory analysis by miRNA expression profiling using microarrays. Expression levels of miRNA candidates will be validated by TaqMan real-time quantitative polymerase chain reaction (RT-PCR).
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| basal cell carcinoma | |||
| non-lesional skin |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Patients with
Basal Cell Carcinoma
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Falk G Bechara, PD Dr. | Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum | Study Director |
| Peter Altmeyer, Prof. Dr. | Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum | Study Chair |
| Michael Sand, Dr. | Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum | Bochum | North Rhine-Westphalia | 44791 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22540308 | Result | Sand M, Skrygan M, Sand D, Georgas D, Hahn SA, Gambichler T, Altmeyer P, Bechara FG. Expression of microRNAs in basal cell carcinoma. Br J Dermatol. 2012 Oct;167(4):847-55. doi: 10.1111/j.1365-2133.2012.11022.x. Epub 2012 Aug 20. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D002280 | Carcinoma, Basal Cell |
| ID | Term |
|---|---|
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
Not provided
Not provided
Not provided
Not provided
Not provided
basal cell carcinoma and non-lesional skin
| D018295 |
| Neoplasms, Basal Cell |