Diagnostic and Prognostic Value of New Biomarkers in Patients With Heart Disease

Diagnostic and Prognostic Value of New Biomarkers in Patients With Heart Disease

The objective of this work is to investigate and then to sequence new biomarkers in the plasma of patients presenting with dyspnea secondary or not to heart failure, and study their diagnostic and prognostic value.

Plasma samples for patients with dyspnea, edema, with or without heart failure; ambulatory or admitted for cardiac decompensation (even with cardiac shock and LVAD) ; or entering a cardiac rehabilitation program, will be prospectively collected.

The objective of this work is to investigate and then to sequence new proteins in the plasma of these patients for diagnostic and prognostic purpose.

Inclusion Criteria:

• Patients presenting with shortness of breath secondary or not to heart failure, even with cardiac shock and LVAD.
• Patients with valvular disease
• chronic stable heart failure.
• post- partum Cardiomyopathy

Exclusion Criteria:

• terminal cancer
• progressive neurological disease
• pregnancy
• opposition of the patient