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| Name | Class |
|---|---|
| Fund for Scientific Research, Flanders, Belgium | OTHER |
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There is strong evidence that our current consumption of salt is the major factor increasing blood pressure (BP). The current salt intake in most countries in the world is 9 to 12 grams per day (g/d), whil the World Health Organization's recommendation is < 5 g/d.
The aims of the present study is to determine if the overconsumption of salt influences the bp in patients with uncontrolled hypertension or frequently elevated bp.
Each study subject will complete questionnaires, and their usual dietary salt intake is estimated from food composition on 3 completed food diaries. This is also compared with a 24-hour urine sample collection.
Based on these results, the study subject receives personal advice to decrease sodium consumption and will change the diet for at least 28 days. During this diet, bp will be measured and food diaries will be completed. After the intervention, a questionnaire and a 24-hour urine sample collection will be collected.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 4-week diet, low in sodium | Experimental | The study subjects go on a 4-week diet, low in sodium. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| A 4-week diet, low in sodium. | Other | Study subjects receive personal advice to decrease sodium consumption and will change his diet for 28 days. Follow up is performed by measuring blood pressure, a 24-hour urine sample collection, diaries and questionnaires. |
| Measure | Description | Time Frame |
|---|---|---|
| Measurement of blood pressure after a 4-week diet, low in sodium. | after 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Life style change after a 4-week diet, low in sodium. | after 4 weeks |
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Inclusion Criteria:
adults, 50 years of age or older with changing blood pressure (bp) with or without drugs and patients with uncontrolled bp despite drugs
An average systolic bp on 2 of the 3 previous visits of 140 mm Hg or more (130 mm Hg for diabetics) and an average diastolic bp of 80 to 100 mm Hg.
Blood analysis (fasting glycaemia, creatinin, total cholesterol, high- density lipoprotein cholesterol) in the last 6 months
At least 3 criteria of the following:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Stefaan Dehenauw, Ph.D, Professor | University Ghent | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Ghent | Ghent | 9000 | Belgium |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D004032 | Diet |
| D012964 | Sodium |
| ID | Term |
|---|---|
| D009747 | Nutritional Physiological Phenomena |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D008672 | Metals, Alkali |
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| D004602 | Elements |
| D007287 | Inorganic Chemicals |
| D019565 | Metals, Light |
| D008670 | Metals |