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| Name | Class |
|---|---|
| Société des Produits Nestlé (SPN) | INDUSTRY |
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Dietary fiber is known to influence bowel function. The investigators hypothesize that the addition of a mixture of fibers to liquid diets will improve bowel function as measured by stool weight.
Liquid diets are the sole source of nutrition for many patients. Consumption of liquid diets is linked to lower stool weight. The objective of this study is to feed liquid diets, with and without added fiber, to healthy human subjects to determine if mixed fiber sources can normalize stool weight. Secondary objectives of the study include measurement of gut microbiota and stool chemistry with fiber addition.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| dietary fiber | Dietary Supplement | mixture of fiber sources added to liquid nutrition product |
|
| Measure | Description | Time Frame |
|---|---|---|
| Stool weight | 5 day fecal collection on last 5 days of 14 day feeding trial | 5 day collection |
| Measure | Description | Time Frame |
|---|---|---|
| fecal microbiota | fecal sample on last day of feeding trial will be collected for microbiota analysis | day 14 of feeding trial |
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Inclusion Criteria:
1.Weight
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Joanne Slavin, PhD | University of Minnesota | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Minnesota | Saint Paul | Minnesota | 55108 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24233256 | Derived | Koecher KJ, Thomas W, Slavin JL. Healthy subjects experience bowel changes on enteral diets: addition of a fiber blend attenuates stool weight and gut bacteria decreases without changes in gas. JPEN J Parenter Enteral Nutr. 2015 Mar;39(3):337-43. doi: 10.1177/0148607113510523. Epub 2013 Nov 14. |
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| ID | Term |
|---|---|
| D004043 | Dietary Fiber |
| ID | Term |
|---|---|
| D004040 | Dietary Carbohydrates |
| D002241 | Carbohydrates |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
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| D010829 |
| Physiological Phenomena |
| D019602 | Food and Beverages |