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The purpose of this study is to determine whether extracorporeal circulation during cardiac surgery has an influence on ADAMTS13-Activity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| with extracorporeal circulation | Patients undergoing cardiac surgery with the use of an extracorporeal circulation | ||
| without extracorporeal circulation | Patients undergoing cardiac surgery without the use of extracorporeal circulation (OPCAB) |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in ADAMTS13-Activity over time | during surgery (at 1and 2 hours after beginning) and within the first 6 days after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Change in ADAMTS13-Antibody over time | during surgery (at 1and 2 hours after beginning) and within the first 6 days after surgery | |
| Change in Platelet count over time | during surgery (at 1and 2 hours after beginning) and within the first 6 days after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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Patients undergoing cardiac surgery at the University Hospital
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Wolfgang Miesbach | Contact | +49696301 | 5051 | wolfgang.miesbach@kgu.de |
| Imke R Reinecke | Contact | ireineck@stud.uni-frankfurt.de |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Johann Wolfgang Goethe University Hospital | Recruiting | Frankfurt am Main | Hesse | 60590 | Germany |
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| time duration of extracorporeal circulation during surgery | during surgery |
| Amount of intraoperative given fluid replacement | during surgery |
| Amount of given blood products (red blood cells) | 24 hours |