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Two to 15% of subjects present dysphagia. In case of normal eso-gastro-duodenal endoscopy, patients with dysphagia are referred for esophageal motility testing. Esophageal manometry is the gold standard to evaluate esophageal motility in absence of esophageal obstruction. Two different techniques are available: the conventional manometry and the high resolution manometry. The second one may improve the diagnostic yield and the tolerance of examination in patients with dysphagia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Conventional manometry | Other |
| |
| High resolution manometry | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Conventional manometry | Device | Conventional esophageal manometry |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of patients correctly diagnosed for esophageal motility disorder | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Tolerability (pain, nausea, cough, anxiety) and side effects (nasal bleeding, vomiting, inhalation, esophageal perforation, cardiac failure) | 24 hours | |
| Duration of examination and study analysis | day 0 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sabine ROMAN, Dr | Unité d'Exploration Fonctionnelle Digestive - Hôpital Edouard Herriot - 69437 Lyon Cedex 03- France | Principal Investigator |
| Stanislas BRULEY DES VARANNES | Service d'Hépato-Gastro-Entérologie - CHU Hôtel Dieu - Place A Ricordeau - 44093 Nantes Cedex - France | Principal Investigator |
| Franck ZERBIB | Service d'Hépato-Gastro-Entérologie - Hôpital Saint-André - 33075 Bordeaux Cedex - France | Principal Investigator |
| Guillaume GOURCEROL | Service de Physiologie Digestive, Respiratoire, Urinaire et Sportive - CHU de Rouen - 76031 Rouen Cedex - France | Principal Investigator |
| Silvana PERRETTA | Pole Hépato- Digestif, Service de Chirurgie digestive et endocrinienne - Nouvel Hôpital Civil - 1 place de l'Hôpital - 67091 Strasbourg cedex - France | Principal Investigator |
| Franck ROPERT | Service d'Hépato-Gastro-Entérologie - CHU Pontchaillou - Rue H. le Guillou - 35033 Rennes cedex - France | Principal Investigator |
| François MION, MD | Service d'Hépato-Gastro-Entérologie, Hôpital de la Croix-Rousse , 69317 Lyon | Principal Investigator |
| Benoit COFFIN, MD | Service d'Hépato-Gastroentérologie, Hôpital Louis Mourier, 92700 Colombes |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Unité d'Exploration Fonctionnelle Digestive - Hopital Edouard Herriot - 69437 LYON Cedex 03 | Lyon | Lyon | 69437 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26832656 | Result | Roman S, Huot L, Zerbib F, Bruley des Varannes S, Gourcerol G, Coffin B, Ropert A, Roux A, Mion F. High-Resolution Manometry Improves the Diagnosis of Esophageal Motility Disorders in Patients With Dysphagia: A Randomized Multicenter Study. Am J Gastroenterol. 2016 Mar;111(3):372-80. doi: 10.1038/ajg.2016.1. Epub 2016 Feb 2. |
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| ID | Term |
|---|---|
| D003680 | Deglutition Disorders |
| ID | Term |
|---|---|
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D010608 | Pharyngeal Diseases |
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| High resolution manometry |
| Device |
High resolution esophageal manometry |
|
| Cost of patient care within the 6 months following the manometry | 6 months |
| Principal Investigator |
| D010038 | Otorhinolaryngologic Diseases |