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Dietary intervention to prevent sarcopenia in elderly people. The objective of this study is to test whether combined nutrient intake plays an important role in stimulation of the muscle protein growth in elderly people; and whether it represent effective strategies to overcome the impaired muscle protein synthesis in elderly when compared with young subjects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| protein (elderly) | Experimental |
| |
| protein and carbohydrate (elderly) | Experimental |
| |
| protein and carbohydrate (young) | Experimental |
| |
| protein and leucine (elderly) | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| protein | Other | 20g protein |
| |
| protein and carbohydrate |
| Measure | Description | Time Frame |
|---|---|---|
| Muscle protein synthesis | Muscle protein synthesis will be expressed as fractional synthetic rate (FSR) by dividing the increment in enrichment in the product, i.e. protein-bound C13phe, by the enrichment of the precursor (=plasma availability). | 6 h postprandial period |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| A. de Lange | Maastricht University Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universiteit Maastricht, Bewegingswetenschappen | Maastricht | Limburg | Netherlands |
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| Label | URL |
|---|---|
| Information about research performed by the Maastricht Muscle Metabolism group at MUMC | View source |
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| ID | Term |
|---|---|
| D011506 | Proteins |
| D002241 | Carbohydrates |
| D007930 | Leucine |
| ID | Term |
|---|---|
| D000602 | Amino Acids, Peptides, and Proteins |
| D000597 | Amino Acids, Branched-Chain |
| D000596 | Amino Acids |
| D000601 | Amino Acids, Essential |
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| Other |
20g protein and 20g carbohydrate |
|
| protein and leucine | Other | 20g protein, 2.5g leucine |
|