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| ID | Type | Description | Link |
|---|---|---|---|
| 2010-021161-71 | EudraCT Number |
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The purpose of this study is to determine whether Adductor-Canal-Blockade is effective at reducing pain and morphine consumption after revision knee arthroplasty.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Adductor-Canal-Blockade with ropivacaine | Experimental |
| |
| Adductor-Canal-blockade with saline | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Adductor-Canal-Blockade with Ropivacaine | Procedure | US-guided Adductor-Canal-Blockade with ropivacaine 7,5 mg/ml |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain during 45 degrees active flexion of the knee | 0-100 mm at a visual analogue scale (VAS), at 4 hours postoperative. | 4 hours postoperative |
| Measure | Description | Time Frame |
|---|---|---|
| Pain during 45 degrees active flexion of the knee | 0-100 mm at a visual analogue scale (VAS), registered at the intervals 1, 2, 4, 6 and 8 hours postoperative, calculated as "the area under the curve" (AUC) for the interval 1-8 hours postoperative. | 1-8 hours postoperative |
| Pain during 45 degrees active flexion of the knee |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Pia Jæger, MD | Rigshospitalet, Denmark | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Anaesthesia and Surgery, HOC, Rigshospitalet, Denmark | Copenhagen | København Ø | 2100 | Denmark |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25386752 | Derived | Jaeger P, Koscielniak-Nielsen ZJ, Schroder HM, Mathiesen O, Henningsen MH, Lund J, Jenstrup MT, Dahl JB. Adductor canal block for postoperative pain treatment after revision knee arthroplasty: a blinded, randomized, placebo-controlled study. PLoS One. 2014 Nov 11;9(11):e111951. doi: 10.1371/journal.pone.0111951. eCollection 2014. |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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| ID | Term |
|---|---|
| D000077212 | Ropivacaine |
| D012965 | Sodium Chloride |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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| Adductor-Canal-blockade with saline | Procedure | US-guided Adductor-Canal-blockade with saline |
|
|
0-100 mm at a visual analogue scale (VAS), at 24 hours postoperative. |
| 24 hours postoperative |
| Pain during rest | 0-100 mm at a visual analogue scale (VAS), registered at the intervals 1, 2, 4, 6 and 8 hours postoperative, calculated as "the area under the curve" (AUC) for the interval 1-8 hours postoperative. | 1-8 hours postoperative |
| Pain during rest | 0-100 mm at a visual analogue scale (VAS), at 24 hours postoperative. | 24 hours postoperative |
| Total morphine consumption | Total morphine consumption at the intervals 0-8, 8-24 and 0-24 hours postoperative. | 0-24 hours postoperative |
| Postoperative nausea | Nausea scores(0-3)registered at 1,2,4,6 and 8 hours postoperative, calculated as mean value for the interval 1-8 hours postoperative. | 1-8 hours postoperative |
| Postoperative nausea | Nausea score(0-3)at 24 hours postoperative. | 24 hours postoperative |
| Postoperative vomiting | Number of vomiting episodes at the intervals 0-8, 8-24 and 0-24 hours postoperative. | 0-24 hours postoperative |
| Zofran consumption | Total zofran consumption at the intervals 0-8, 8-24 and 0-24 hours postoperative. | 0-24 hours postoperative |
| Sedation | Sedation score (0-3) registered at 1,2,4,6 and 8 hours postoperative, calculated as the mean value for the interval 1-8 hours postoperative. | 1-8 hours postoperative |
| Sedation | Sedation score (0-3) at 24 hours postoperative. | 24 hours postoperative |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D000588 |
| Amines |
| D002712 | Chlorides |
| D006851 | Hydrochloric Acid |
| D017606 | Chlorine Compounds |
| D007287 | Inorganic Chemicals |
| D017670 | Sodium Compounds |