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| ID | Type | Description | Link |
|---|---|---|---|
| 2013-000663-83 | EudraCT Number | ||
| H-3-2013-039 | Other Identifier | Regional Ethics Committee, Capital region of Denmark |
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The investigators want to explore the analgesic effect of Adductor Canal Blockade (a peripheral nerve block) in high pain responding patients after arthroscopic knee surgery. The investigators hypothesize that the nerve block will have an abrupt analgesic effect.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention group, block no. 1 - Ropivacain | Experimental | Adductor-Canal-Block no.1: 30mL ropivacaine (7.5 mg/ml) when postoperative VAS-score is > 40mm (on a 0-100 mm VAS-scale) during a 45 degree active flexion of the knee. Adductor-Canal-Block no.2: after 45 min (t45) - 30mL isotonic saline. |
|
| Control group, block no. 1 - saline | Sham Comparator | Adductor-Canal-Block no.1: 30mL isotonic saline when postoperative VAS-score is above 40mm (on a 0-100 mm VAS-scale) during a 45 degree active flexion of the knee. Adductor-Canal-Block no.2: after 45 min (t45) - 30mL ropivacaine (7.5 mg/ml) |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intervention group, block no. 1 - Ropivacain | Procedure | Intervention group: 1. block ropivacaine - 2. block saline |
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| Measure | Description | Time Frame |
|---|---|---|
| Pain score during 45 degree flexion of the knee | Pain score during flexion of the knee 45 min. after nerve block | 45 minutes after nerve block |
| Measure | Description | Time Frame |
|---|---|---|
| Pain score | pain score at rest: time 0,15,30,45,60,75,90 min. after first nerve block pain score during flexion of the knee: time 0,15,30,45,60,75,90 min. after first nerve block pain score during mobilisation (5m walk): 45 and 90 min after nerve block | 0-90 min. after first nerveblock |
| muscle strength |
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Inclusion Criteria:
Arthroscopic knee surgery, if reconstruction of Anterior Cruciate Ligament only hamstring graft 18-80 years of age BMI 18-40 ASA I-III written Consent
Exclusion Criteria:
Unable to communicate in danish, allergic reactions toward any study medication pregnancy alcohol/drug abuse daily opioid consumption scin infection (injection site)
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| Name | Affiliation | Role |
|---|---|---|
| Malene Espelund, MD | Glostrup University Hospital, University of Copenhagen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Amager Hospital, University of Copenhagen, Denmark | Copenhagen | Copenhagen, Amager | 2300 | Denmark |
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| Control group: 1. block - saline | Procedure | Control group: 1. block saline - 2. block ropivacaine |
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patients accesses muscle strength during walk |
| 45 and 90 min after nerve block |
| Opioid consumption | 0-90 min after nerve block |