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This randomized trial is examining whether a treatment called cognitive remediation is more effective when it is paired with a social and functional skills training component.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cognitive remediation | Experimental | Cognitive remediation |
|
| Functional Adaptive Skills Training | Active Comparator | Functional and social skills group treatment |
|
| Combined Treatment | Active Comparator | Combined cognitive remediation and functional adaptive skills training |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cognitive Remediation | Behavioral | Computer-based, therapist-lead cognitive remediation |
|
| Measure | Description | Time Frame |
|---|---|---|
| neurocognition | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| functional competence | performance-based measures of functional and social competence | 12 weeks |
| neurocognition | 24 weeks | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Christopher R Bowie, PhD | Queen's University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Queen's University | Kingston | Ontario | K7L 3N6 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22581070 | Derived | Bowie CR, McGurk SR, Mausbach B, Patterson TL, Harvey PD. Combined cognitive remediation and functional skills training for schizophrenia: effects on cognition, functional competence, and real-world behavior. Am J Psychiatry. 2012 Jul;169(7):710-8. doi: 10.1176/appi.ajp.2012.11091337. |
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| ID | Term |
|---|---|
| D012559 | Schizophrenia |
| D011618 | Psychotic Disorders |
| ID | Term |
|---|---|
| D019967 | Schizophrenia Spectrum and Other Psychotic Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D000072466 | Cognitive Remediation |
| ID | Term |
|---|---|
| D001521 | Behavior Therapy |
| D011613 | Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |
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| FAST | Behavioral | Functional adaptive skills training. Group treatment to foster the acquisition of social and adaptive skills |
|
| neurocognition |
| 36 weeks |
| functional competence | 24 weeks |
| functional competence | 36 weeks |