Localizing the Epileptogenic Zone With High Resolution Electroencephalography

Etude de la Performance Diagnostique de l'EEG-Haute Résolution Sur la Localisation de la Zone épileptogène Pour le Traitement Chirurgical Des épilepsies Partielles Pharmaco-résistantes

Multicenter prospective study comparing the diagnosis value of high-resolution EEG and depth-EEG to localize the epileptogenic zone in drug resistant partial epilepsies.

Inclusion Criteria:

• medically intractable patial epilepsy confirmed by video-EEG recordings of epileptic seizures.
• Depth EEG (Stereo-EEG) required to delineate the epileptogenic zone and define the surgical procedure.
• full informed consent of the patient (or of his/ her legal representative)
• 15 year or older patient

Exclusion Criteria:

• contraindication to cortectomy

• contraindication to depth-EEG

• indication of epilepsy surgery without depth-EEG monitoring

• high grade glioma, arterio-veinous malformations

  • pregnancy
  • history of severe cardio-vascular event (coronaropathy, stroke)