Electrohaemodynamic Activity in Epileptic Children : Combined Video-EEG and Near-infrared Spectroscopy (NIRS) Analysis

Electrohaemodynamic Activity in Epileptic Children: Combined Video-EEG and Near-infrared Spectroscopy (NIRS) Analysis

Evaluate the contribution of multimodal high-resolution EEG-NIRS electrical and local haemodynamic analysis to spatial localization of epileptogenic foci

This study is designed to evaluate the contribution of multimodal high-resolution EEG-NIRS electrical and local haemodynamic analysis (HR-EEG, HR-NIRS) to spatial localization of epileptogenic foci in order to perform multimodal mapping and localization of interictal spikes (by HR-EEG source reconstruction) with the clinical prospects of guiding the SEEG electrode implantation strategy prior to surgery in children with drug-refractory partial epilepsy.

Inclusion Criteria:

• Children between the ages of 6 and 18 years
• with drug-refractory partial epilepsy, presenting interictal spikes on standard EEG recordings.

Exclusion Criteria:

• Children with a serious congenital malformation.
• Refusal from one of the parents or the child.
• Children with generalized epilepsy or diffuse interictal spikes.
• Children with severely impaired general status and vital functions.
• Children with dermatosis of the face or scalp.
• Children under the age of 6 years or adults over the age of 18 years.