The study hypothesis tested is that broccoli sprouts are effective at altering the urinary levels of metabolites of the hepatocarcinogen aflatoxin B1 and of the air-borne pollutant phenanthrene in residents of Qidong, PRC, where exposures are unavoidable and high. The study will evaluate which of two formulations of broccoli sprouts beverage, glucoraphanin-rich or sulforaphane-rich, exhibits the best bioavailability and is most effective at modulating the biomarkers.

Inclusion Criteria:

• Adults aged 25-65 in good general health with no history of a chronic illness
• normal liver function tests (ALT, AST, bilirubin)
• normal renal function tests (creatinine, BUN, urinalysis)
• serum alpha-fetoprotein negative

Exclusion Criteria:

• personal history of cancer, except for non-melanoma skin cancer
• use of prescribed medications
• hepatomegaly by clinical exam
• unwillingness to avoid cruciferous vegetable consumption for the duration of the study
• for women, a positive pregnancy test.