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The purpose of this study is to determine if daily supplementation with 2000 International Units of Vitamin D will improve hemoglobin A1c in uncontrolled type 2 diabetics.
Vitamin D is typically understood to support musculoskeletal health when administered concomitantly with calcium. A number of recent studies suggest, however, that this important nutrient may play a significant role in many pathophysiological processes, including diabetes mellitus. With the prevalence of diabetes mellitus ever increasing, novel mechanisms for controlling blood glucose and hemoglobin A1c are being sought to help prevent the costly and debilitating complications of this chronic disease.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Vitamin D 2000 international units daily | Experimental |
| |
| Vitamin C 500mg daily | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vitamin D3 2000 international units daily | Dietary Supplement | Vitamin D3 2000 international unit tablets once daily for 3 months |
|
| Measure | Description | Time Frame |
|---|---|---|
| Hemoglobin A1c | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mate M Soric, PharmD | ProMedica Health System | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Flower Hospital Family Medicine Residency | Sylvania | Ohio | 43560 | United States | ||
| Center for Health Services |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22018074 | Derived | Soric MM, Renner ET, Smith SR. Effect of daily vitamin D supplementation on HbA1c in patients with uncontrolled type 2 diabetes mellitus: a pilot study. J Diabetes. 2012 Mar;4(1):104-5. doi: 10.1111/j.1753-0407.2011.00164.x. No abstract available. |
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| Vitamin C 500mg daily | Dietary Supplement | Vitamin C 500mg tablets once daily for 3 months |
|
| Toledo |
| Ohio |
| 43606 |
| United States |
| Toledo Hospital Family Medicine Residency | Toledo | Ohio | 43606 | United States |
| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| ID | Term |
|---|---|
| D001205 | Ascorbic Acid |
| ID | Term |
|---|---|
| D013400 | Sugar Acids |
| D000144 | Acids, Acyclic |
| D002264 | Carboxylic Acids |
| D009930 | Organic Chemicals |
| D006880 | Hydroxy Acids |
| D002241 | Carbohydrates |
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