Pulmonary Rehabilitation in Patients Before Lung Transplantation (LTx)

Effects of a Complex Pulmonary Rehabilitation Program on Patients With End Stage Lung Diseases Undergoing Evaluation for Lung Transplantation (Pre-LTx)

The purpose of this study is to study the effects of a complex pulmonary rehabilitation program on mobility measured by 6 minute walking distance (6MWD) and physical activity, measured via Dynaport and Actibelt Aktivitätsmonitor, dyspnoea (VAS), quality of life (HRQL (SF36, EuroQul)), anxiety and depression (HADS)and PaCO2-behavior under physical activity.

Inclusion Criteria:

• pre-LTx (listed for lung-transplantation or currently undergoing evaluation)
• COPD Stadium IV GOLD
• α-1-Antitrypsin-deficiency-Emphysema
• respiratory Insufficiency
• oxygen therapy (LTOT)

Exclusion Criteria:

• serious Exacerbation (Symptoms longer than three days, change of therapy, e.i. antibiotics, steroids) during the last four weeks before rehabilitation
• clinical signs of manifest heart insufficiency
• acute coronar syndrome
• left heart insufficiency(EF < 40%)
• missing Compliance