Exercise and Glycemic Control in Type 2 Diabetes

Defining the Optimal Exercise Program to Improve Glycemic Control in Various Stages of Type 2 Diabetes.

Hyperglycemia is an independent risk factor for the development of diabetic complications in type 2 diabetes. Exercise improves glycemic control, however, the role of exercise characteristics (e.g. intensity, type of exercise, timing, frequency) remains to be elucidated.

This study aims to assess the effect of several exercise characteristics on hyperglycemia in various subgroups of type 2 diabetes patiënts.

Impaired glucose tolerant subjects

Inclusion Criteria:

• BMI 25 - 35 kg/m2
• Impaired Glucose Tolerant (according to ADA guidelines)

Exclusion Criteria:

• Cardiac disease (cardiac event in the last 5 years)
• Type 2 diabetes
• Use of orale blood glucose lowering medication or exogenous insulin
• HbA1c >10%

Insulin treated type 2 diabetes patients

Inclusion Criteria:

• BMI 25 - 35 kg/m2
• Insulin therapy
• diagnosed with type 2 diabetes >2 yr

Exclusion Criteria:

• Cardiac disease (cardiac event in the last 5 years)
• HbA1c >10%

Type 2 diabetes patients on oral blood glucose lowering medication

Inclusion Criteria:

• BMI 25 - 35 kg/m2
• diagnosed with type 2 diabetes >2 yr

Exclusion Criteria:

• Cardiac disease (cardiac event in the last 5 years)
• HbA1c >10%
• use of exogenous insulin