Fatty Liver and Ectopic Fat in Overweight and Obese Patients

Fatty Liver and Ectopic Fat in Overweight and Obese Patients

The aim of the study is to find new clinico-biological and medical imaging parameters associated with non alcoholic steatohepatitis in overweight and obese patients.

Non invasive assessment of liver fibrosis and liver inflammation and steatosis is clinically relevant in patients exposed to non alcoholic fatty liver diseases.

The aim of the study is to find new clinico-biological and medical imaging parameters associated with non alcoholic steatohepatitis in overweight and obese patients.

Fatty liver and ectopic fat accumulation will be particularly assessed.

Inclusion Criteria:

• BMI between 25 and 40
• ALAT level superior to normal level even after 3 months of diet
• alcohol consumption < 20 g/j for women and < 30 g/j for men

Exclusion Criteria:

• HIV, hepatitis B virus, hepatitis C virus positive
• known hemochromatosis
• glycemia > 1.26 g/L or under anti-diabetic treatment