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This is a single centre prospective open-label, non-randomised pilot study whose aim is to identify MRI parameters to better evaluate inflammation and liver fibrosis and thus, in the near future, to avoid the need for liver biopsy.
To achieve this:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients requiring a liver biopsy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 2 additional MRI sequences | Other |
| ||
| An additional blood sample |
| Measure | Description | Time Frame |
|---|---|---|
| To determine a correlation coefficient > 0.80, alpha 0.05 and beta 0.20 between the MRI markers relevant. | Baselines |
| Measure | Description | Time Frame |
|---|---|---|
| To determine the correlation between the unsaturated fat measurements and MRI Lipidomics Spectro analysis. | Baselines |
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Inclusion Criteria:
Exclusion Criteria:
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Overweight patients or patients with type 2 diabetes or obese patients (who present a liver anomaly and should undergo bariatric surgery)
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Samia HAMZA | Contact | 3 80 29 37 50 | +33 | samia.hamza@chu-dijon.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de DIJON | Dijon | 21079 | France |
|
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| ID | Term |
|---|---|
| D050177 | Overweight |
| D003924 | Diabetes Mellitus, Type 2 |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
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| Other |
|
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D004700 | Endocrine System Diseases |