Benefit of Complex Fractionated Atrial Electrograms Elimination in Atrial Fibrillation Ablation

Benefit of Complex Fractionated Atrial Electrograms Elimination in Atrial Fibrillation Ablation

The aim of this study is to evaluate whether performing complex fractionated atrial electrograms ablation improves outcomes in persistent or atrial fibrillation ablation.

Inclusion Criteria:

• Patients with persistent (more than 7 days, or less than 7 days needing pharmacologic or electric cardioversion)
• Presence of atrial fibrillation at the beginning of the procedure

Exclusion Criteria:

• Hypo or hyperthyroidism
• Persistent long-lasting or non-defined duration atrial fibrillation
• Hypertrophic myocardiopathy
• Implantable defibrillation or pacemaker implanted
• Moderate or severe mitral valve disease or mitral prosthetic valve
• Ejection fraction less than 30%
• Left atrial anteroposterior diameter more than 50 mm.
• Previous atrial fibrillation ablation
• Contraindication to anticoagulation
• Left atrium thrombus
• Current infective disease or sepsis
• Pregnant women
• Current unstable angor
• Acute myocardial infarction in last 3 months
• Atrial fibrillation secondary to ionic disturbance, thyroids disease or secondary to any other reversible or non cardiovascular disease
• Reduced expectancy of life (less than 12 months)
• Patient participating in another clinical study that investigates a drug or device
• Psychologically unstable patient or denies to give informed consent
• Any cause that contraindicate ablation procedure or antiarrhythmic drug