Investigating Physiological Adaptations to Weight Loss

An Investigation of Physiological Adaptations Contributing to Weight Regain After Weight Loss

The purpose of this study is to examine the effect of diet-induced weight loss on the levels of circulating nutrients and hormones which are involved in feelings of hunger and satiety.

Inclusion Criteria:

• males and post-menopausal females
• aged over 18 years
• BMI 27-40kg/m2
• weight-stable

Exclusion Criteria:

• major comorbid medial condition (including diabetes)
• taking medications known to affect weight
• smoking