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The purpose of this study is to study circadian rhythms, or daily cycles of sleep, wake, and activity. The investigators hope to learn how disturbed sleep in Alzheimer's Disease relates to changes in activity cycles, and how sleep disturbances may affect your daytime alertness.
This project selects patients suffering from memory problems, or voluntary to be in our Control Group. There are three parts to this study: Sleep Diaries, Behavioral Questionnaire, and Activity Recordings
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Other | Behavioral Questionnaire Sleep Recordings Genetic analysis |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Analysis of sleep disturbance | Other | Behavioral Questionnaire Sleep Recordings Genetic analysis |
|
| Measure | Description | Time Frame |
|---|---|---|
| assessment of apathy | at day 0, just after inclusion |
| Measure | Description | Time Frame |
|---|---|---|
| assessment of sleep disturbance | during a week, between day 0 and day 7 | |
| determine a genetic relationship between sleep disturbance and alzheimer disease | after all genetic analyses of the study |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Philippe ROBERT | Centre Hospitalier Universitaire de Nice | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Mémoire de Ressources et de Recherche, CHU de Nice | Nice | 06000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31267124 | Result | Ettore E, Bakardjian H, Sole M, Levy Nogueira M, Habert MO, Gabelle A, Dubois B, Robert P, David R. Relationships between objectives sleep parameters and brain amyloid load in subjects at risk for Alzheimer's disease: the INSIGHT-preAD Study. Sleep. 2019 Sep 6;42(9):zsz137. doi: 10.1093/sleep/zsz137. |
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| ID | Term |
|---|---|
| D000544 | Alzheimer Disease |
| D020447 | Parasomnias |
| D053609 | Lethargy |
| D008569 | Memory Disorders |
| ID | Term |
|---|---|
| D003704 | Dementia |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| D024801 |
| Tauopathies |
| D019636 | Neurodegenerative Diseases |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
| D012893 | Sleep Wake Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |