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| ID | Type | Description | Link |
|---|---|---|---|
| 1-47-12225-05-1 |
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| Name | Class |
|---|---|
| Merck Sharp & Dohme LLC | INDUSTRY |
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The purpose of this study is to evaluate etoricoxib efficacy in pain control, leg stiffness and functional recovery of patients suffering acute Achilles tendinopathy.
It is hypothesized that etoricoxib (120mg orally/day/7 days) efficacy is not inferior to diclofenac (150mg orally /day/7 days) for pain control in subjects suffering acute Achilles tendinopathy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| etoricoxib | Experimental | etoricoxib (ETO) group (n=28) treated with etoricoxib 120 mg/day orally for 7 days |
|
| diclofenac | Active Comparator | diclofenac (DIC) group (n=28) received diclofenac 150 mg/day/7 days orally. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| etoricoxib | Drug | etoricoxib (ETO) group (n=28) treated with etoricoxib 120 mg/day orally for 7 days |
|
| Measure | Description | Time Frame |
|---|---|---|
| The pre-defined primary efficacy endpoint of the study is a 100-mm pain visual analog scale (P-VAS), where 0= no pain; 100= extreme pain. | 1 week |
| Measure | Description | Time Frame |
|---|---|---|
| The secondary study endpoints includes: the VISA-A Questionnaire, the Achilles Tendinopathy Scoring System (ATSS), PGART using a 5-point Likert scale and leg functional stiffness. | 1 week |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Argentine Tennis Association | Buenos Aires | Argentina |
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| ID | Term |
|---|---|
| D010146 | Pain |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D000077613 | Etoricoxib |
| D004008 | Diclofenac |
| ID | Term |
|---|---|
| D013450 | Sulfones |
| D013457 | Sulfur Compounds |
| D009930 | Organic Chemicals |
| D011725 | Pyridines |
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| diclofenac | Drug | diclofenac (DIC) group (n=28) received diclofenac 150 mg/day/7 days orally. |
|
| D006573 |
| Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D010648 | Phenylacetates |
| D000146 | Acids, Carbocyclic |
| D002264 | Carboxylic Acids |