Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to determine whether Tendoactive, eccentric training, or the combination or both could be effective in the treatment of Achilles tendinopathy.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Tendoactive | Experimental | Tendoactive dosage: 3 capsules per day |
|
| Eccentric training | Active Comparator | Protocol published by Alfredson et al 1998 (Am J Sports Med 1998 26: 360) |
|
| Tendoactive and eccentric training | Active Comparator | Tendoactive dosage: 3 capsules per day. Eccentric training: protocol described by Alfredson et al 1998 (Am J Sports Med 1998 26: 360) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tendoactive | Drug | Food supplement containing mucopolysaccharides, type I collagen and vitamin C |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline in VISA-A score at 12 weeks | Functional impairment of the Achilles tendon is measured using VISA-A score. Score of patient-related outcome measure: Achilles tendon: VISA-A [0=worse, 100=perfect] derived from eight validated questions on pain and function during activities of daily living | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Pain level at rest [VAS 0-10] | 0, 6, 12 weeks | |
| Pain level at exertion [VAS 0-10] | 0, 6, 12weeks | |
| Achilles transverse thickness by ultrasound |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CMI | Barcelona | Barcelona | Spain | |||
| CEARE |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 9617396 | Background | Alfredson H, Pietila T, Jonsson P, Lorentzon R. Heavy-load eccentric calf muscle training for the treatment of chronic Achilles tendinosis. Am J Sports Med. 1998 May-Jun;26(3):360-6. doi: 10.1177/03635465980260030301. | |
| 28053674 | Derived | Balius R, Alvarez G, Baro F, Jimenez F, Pedret C, Costa E, Martinez-Puig D. A 3-Arm Randomized Trial for Achilles Tendinopathy: Eccentric Training, Eccentric Training Plus a Dietary Supplement Containing Mucopolysaccharides, or Passive Stretching Plus a Dietary Supplement Containing Mucopolysaccharides. Curr Ther Res Clin Exp. 2016 Nov 18;78:1-7. doi: 10.1016/j.curtheres.2016.11.001. eCollection 2016. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Eccentric training | Behavioral | Eccentric training program published by Alfredson et al 1998 (Am J Sports Med 1998 26: 360) |
|
Ultrasound evaluation of Achilles tendon. Maximum thickness will be recorded in the midportion of the affected Achilles tendon |
| 0, 6, 12 weeks |
| SF-36 v2 quality of life survey | 0, 12 weeks |
| Patient satisfaction | Patient satisfaction will be evaluated using a subjective questionnaire. | 6, 12 weeks |
| Esplugues de Llobregat |
| Barcelona |
| 08950 |
| Spain |
| Clínica CEMTRO | Madrid | Madrid | Spain |
| AMS - Centro de Ejercicio | Málaga | Malaga | Spain |
| Centro de Medicina y Deporte | Toledo | Toledo | Spain |
| Clínica Traumatológica | Valladolid | Valladolid | Spain |