Investigation of Dental Plaque and Gingival Index

Investigation of Dental Plaque and Gingival Index

Investigation of inhibitory effect of prototype toothpaste on dental plaque formation via modified gingival margin plaque index method.

Inclusion Criteria:

• Be aged 18 to 65 years inclusive
• Have a minimum of 20 natural uncrowned teeth (excluding 3rd molars) present
• Give written informed consent
• Be in good general health
• Must discontinue oral hygiene for 24-hrs.after initial appointment.
• No known history of allergy to personal care/consumer products or their ingredients, relevant to any ingredients in the test products as determined by the dental/medical professional monitoring the study

Exclusion Criteria:

• Medical condition which requires pre-medication prior to dental visits/procedures
• Advanced periodontal disease
• 5 or more decayed, untreated dental sites
• Diseases of the soft or hard oral tissues
• Orthodontic appliances
• Abnormal salivary function
• Use of drugs that can currently affect salivary flow
• Use of antibiotics one (1) month prior to or during this study
• Use of any over the counter medications other than analgesics (i.e. aspirin, ibuprofen, acetaminophen, naproxyn)
• Pregnant or breastfeeding.
• Participation in another clinical study in the month preceding this study
• Allergic to common dentifrice ingredients.
• Immune compromised individuals (HIV, AIDS, immuno suppressive drug therapy)