Comparative Efficacy of a Toothpaste That Reduces Plaque and Gingivitis

Comparative Efficacy of a Toothpaste That Reduces Plaque and Gingivitis

The objective of this study is to evaluate the performance of two toothpastes in controlling established gingivitis and dental plaque in adults.

Inclusion Criteria:

• Availability for the six-month duration of the study.
• Good general health.
• Minimum of 20 uncrowned permanent natural teeth (excluding third molars).
• Initial gingivitis index of at least 1.0 as determined by the use of the Loe and Silness Gingival Index.
• Initial plaque index of at least 1.5 as determined by the use of the Quigley and Hein Plaque Index (Turesky Modification).
• Signed Informed Consent Form.

Exclusion Criteria:

• Presence of orthodontic bands.
• Presence of partial removable dentures.
• Tumor(s) of the soft or hard tissues of the oral cavity.
• Advanced periodontal disease (purulent exudate,tooth mobility, and/or extensive loss of
• periodontal attachment or alveolar bone).
• Five or more carious lesions requiring immediate restorative treatment.
• Use of antibiotics any time during the one month prior to entry into the study.
• Participation in any other clinical study or test panel within the one month prior to entry
• into the study.
• Pregnant women or women who are breast feeding.
• Receive a dental prophylaxis in the past two weeks prior to baseline examinations.
• History of allergic to personal care/consumer products or their ingredients.
• Taking any prescription medicines. That might interfere with the study outcome.
• Individuals with an existing medical condition which prohibits them from not eating or drinking for periods up to 4 hours.