The purpose of this study is to determine if AzaSite Plus is effective and safe for the treatment of blepharoconjunctivitis compared to AzaSite alone and Dexamethasone alone.

Inclusion Criteria:

• Have a clinical diagnosis of blepharoconjunctivitis
• Must be willing to discontinue contact lens wear for the duration of the study
• Have best corrected visual acuity of 6/24 in both eyes
• Have IOP less than or equal to 25 mmHg in either eye

Exclusion Criteria:

• Have known sensitivity or poor tolerance to any component of the study medications
• Have a history of eyelid and/or ocular surgery and/or have had ocular surgical intervention within 6 months prior to visit 1 or during the study and/or a history of refractive surgery within 6 months
• Have worn contact lenses 72 hours prior to visit 1 and/or need to wear contact lenses for the duration of the study
• Have used any topical ophthalmic solutions including tear substitutes within 2 hours of enrollment
• Use of any eye make-up during the study
• Have any uncontrolled systemic disease or debilitating disease
• Have been diagnosed with glaucoma
• Have any clinically significant cardiovascular disorders
• Have any history of liver or kidney disease resulting in persisting dysfunction
• Have prior (within 30 days of beginning study treatment) or anticipated concurrent use of an investigational drug or device