Safety and Efficacy Study of AzaSite® in Subjects With Blepharitis

A Multi-Center, Open-Label Study Evaluating the Cytokine and Eyelid Margin Bacterial Load Levels of Subjects Diagnosed With Chronic Blepharitis Following Dosing With AzaSite® (Azithromycin Ophthalmic Solution) 1%

The purpose of this study is to evaluate the safety and efficacy of AzaSite® ophthalmic solution, 1% on signs & symptoms of blepharitis and tear cytokine and eyelid bacterial load levels

Inclusion Criteria:

• Diagnosis of moderate to severe chronic blepharitis
• If female of childbearing potential, are non-pregnant and non-lactating

Exclusion Criteria:

• Had ocular surface surgery (LASIK, refractive, etc.) within the past year
• Unwilling to discontinue use of contact lenses during the study
• Have glaucoma
• Unable or unwilling to withhold the use of lid scrubs during the study
• Have a serious systemic disease or uncontrolled medical condition that in the judgment of the investigator could confound study assessments or limit compliance
• Currently using any preserved topical ocular medications (with the exception of unpreserved tear substitutes) at the time of entry into the study or during study participation