Pilot Study: Is Overactive Bladder Caused by Subacute Urinary Tract Infections?

Pilot Study: Is Overactive Bladder Caused by Subacute Urinary Tract Infections?

The purpose of this study is to look for evidence of bacteria in the urine or bladder of people with overactive bladder. Because you do not have overactive bladder, your participation in this study will be used as a comparison to those who have overactive bladder.

Inclusion Criteria:

• Urge urinary incontinence based on clinical history and bladder diary; subjects must have 3 or more urge incontinence episodes/day and 10 or more voids/day.
• 21 years or older
• Healthy volunteers for control subjects

Exclusion Criteria:

• Active cystitis performed on a catheterized urine specimen
• Known or suspected correctable etiology for her urge incontinence
• History of urinary tract stones, foreign bodies or malignancy
• History of recurrent Urinary Tract Infections
• Pregnant women, children
• Evidence of urge urinary incontinence or more than 1 episode of stress incontinence/day by control subject