OAB and the Microbiome

Trends in the Microbiome Profiles of Women With Urgency and Frequency Syndrome, With or Without Pelvic Pain?

To determine differences in the urinary microbiomes, identified by polymerase change reaction (PCR) (UTIP™), of female patients with urgency and frequency syndrome with or without pelvic pain (Group A) compared to female controls without symptoms of lower urinary tract symptoms (LUTS) (Group B).

Inclusion Criteria:

• 18 y/o-90 y/o
• Able to consent
• Group A only: Urgency and Frequency Syndrome or OAB only. UDI-6 answer of "moderately" to "quite a bit" on questions 1 or 2.
• Group B only: Urinary Distress Inventory 6 (UDI-6) answer "not at all" or "somewhat" for questions 1 or 2.

Exclusion Criteria:

• Pregnant
• Pelvic radiation
• Urinary retention (>200 ml)
• Renal calculi
• Recurrent urinary tract infection (UTI) (2 in 6 months), or
• Current UTI
• Immunosuppressed or radiation history
• Neurologic disorder