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| Name | Class |
|---|---|
| Robert C. Atkins Foundation | OTHER |
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To test the effects of a modified Atkins high fat diet on endothelial function, insulin resistance and energy balance.
To test the effects of a modified Atkins high fat diet on endothelial function, insulin resistance and energy balance.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| AFN A | Placebo Comparator | High Fat Diet Placebo |
|
| AFN B | Experimental | MUFA |
|
| AFN C | Experimental | PUFA |
|
| AFN D | Experimental | SFA |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Placebo | Dietary Supplement | Placebo |
| |
| MUFA |
| Measure | Description | Time Frame |
|---|---|---|
| endothelial function | 4 months |
| Measure | Description | Time Frame |
|---|---|---|
| energy balance and body composition | 4 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Heidi J Silver, PhD | Vanderbilt University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Vanderbilt University | Nashville | Tennessee | 37232 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29382504 | Derived | Niswender KD, Fazio S, Gower BA, Silver HJ. Balanced high fat diet reduces cardiovascular risk in obese women although changes in adipose tissue, lipoproteins, and insulin resistance differ by race. Metabolism. 2018 May;82:125-134. doi: 10.1016/j.metabol.2018.01.020. Epub 2018 Jan 31. | |
| 24559846 | Derived | Silver HJ, Kang H, Keil CD, Muldowney JA 3rd, Kocalis H, Fazio S, Vaughan DE, Niswender KD. Consuming a balanced high fat diet for 16 weeks improves body composition, inflammation and vascular function parameters in obese premenopausal women. Metabolism. 2014 Apr;63(4):562-73. doi: 10.1016/j.metabol.2014.01.004. Epub 2014 Jan 17. |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| Dietary Supplement |
MUFA |
|
| PUFA | Dietary Supplement | PUFA |
|
| SFA | Dietary Supplement | SFA |
|
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |