The purpose of this study is to determine if the Punctum Plug Delivery System (PPDS) is safe and effective in controlling intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Inclusion Criteria:

• Over 18 yrs with open-angle glaucoma or ocular hypertension
• Subjects who have a best-corrected visual acuity of 20/100 or better.

Exclusion Criteria:

• Uncontrolled medical conditions.
• Subjects who wear contact lenses.
• Subjects requiring chronic topical artificial tears, lubricants, and/or requiring any other chronic topical medications.
• Subjects who have a history of chronic or recurrent inflammatory eye disease.