Acute Phase Proteins as Early Markers in Sepsis

Acute Phase Proteins as Early Markers in Sepsis

Monitoring of different serumproteins after severe trauma and during trauma-induced sepsis.

• Trial with surgical intervention

Inclusion criteria:

• Patients with severe trauma (ISS score > 16), both genders, patients on ICU

Exclusion criteria:

• Moribund patients (pH <7,1, lactate >15mmol, Basedeficit > 15mEq/L, severe heart or liver injuries, GCS never over 5 after trauma)
• Severe head injuries (AIS head >4)
• Patient with severe infectious diseases, or diseases which severely affect the immune system (diabetes, Alkohol or nicotine abuse)
• Non-german speaking patients