Randomized, Controlled Study to Investigate the Effect of Neuromuscular Electrical Stimulation (NMES) on Muscle Metabolism of Abdominal Surgical Patients

The Effect of Neuromuscular Electrical Stimulation on Muscle Metabolism of Major Abdominal Surgical Patients

Skeletal muscle atrophy is associated with catabolic conditions such as major surgical interventions and leads to reduced muscle strength, increased clinical complications and prolonged convalescence. Several studies revealed immobilisation as a major stimulus for muscle wasting in severely ill patients. This study investigates the potency of neuromuscular electrical stimulation on skeletal muscle growth factors and degradation processes in major abdominal surgery patients.

Inclusion Criteria:

• intended for major abdominal surgery
• more than 18 years old

Exclusion Criteria:

• neuromuscular diseases
• immobility before surgery
• arterial occlusive disease Fontaine stadium IV
• clinical or laboratory signs of inflammation or sepsis
• cachexia
• diseases of the musculoskeletal systems contraindicating electrical stimulation