Cannabinoid Receptor Function & Alcoholism | NCT00624715 | Trialant

Cannabinoid Receptor Function & Alcoholism | NCT00624715 | Trialant

Sponsor/Collaborators Module

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
THC	Active Comparator	High dose: 0.036 mg/kg (2.5 mg in a 70 kg individual) IV (in the vein) dissolved in ethanol.Equivalent to smoking a full joint Low dose: 0.018 mg/kg (1.25 mg in a 70kg individual)IV (in the vein) dissolved in ethanol.Equivalent to smoking ½ of a joint Very low dose: 0.0036 mg/kg (0.25 mg in a 70 kg individual)IV (in the vein) dissolved in ethanol.Equivalent to smoking 1/10 of a joint	Drug: THC
Placebo	Placebo Comparator	Placebo: Small amount of ethanol IV (in the vein), (quarter teaspoon).	Drug: Placebo

Interventions

Name	Type	Description	Arm Group Labels	Other Names
THC	Drug	High dose: 0.036 mg/kg (2.5 mg in a 70 kg individual)IV (in the vein) dissolved in ethanol. Equivalent to smoking a full joint Low dose: 0.018 mg/kg (1.25 mg in a 70kg individual) IV (in the vein) dissolved in ethanol.Equivalent to smoking ½ of a joint Very low dose: 0.0036 mg/kg (0.25 mg in a 70 kg individual)IV (in the vein) dissolved in ethanol. Equivalent to smoking 1/10 of a joint

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Clinician Administered Dissociative Symptoms Scale, Visual Analog Scale ("High" rating), Rey Auditory Verbal Learning Test		Baseline, +15, +25 (RAVLT only), +70, +240

Contacts/Locations Module

Condition Browse Module

Intervention Browse Module