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| Name | Class |
|---|---|
| Welch Foods Incorporated | INDUSTRY |
| U.S. Highbush Blueberry Council | OTHER |
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To evaluate the effect of supplemented berry fruit juice and whole fruit berry powder on memory performance and brain function in older adults
Randomized trials involving daily supplementation with berry fruits in older adults with early memory changes. The berry products include Concord grape juice, blueberry juice, and whole fruit blueberry powder. Supplementation periods are 12 and 16 weeks, depending on berry product. The Aims of the studies are to assess effects on cognitive performance and in a subset of participants, in brain activity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| grape juice active intervention | Active Comparator | Concord grape juice administered daily for 12 or 16 weeks |
|
| juice placebo | Placebo Comparator | berry placebo juice administered daily for 12 or 16 weeks |
|
| blueberry juice active intervention | Active Comparator | wild blueberry juice administered daily for 12 weeks |
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| blueberry powder intervention | Active Comparator | whole fruit blueberry powder administered daily for 16 weeks |
|
| powder placebo | Placebo Comparator | placebo powder administered daily for 16 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Concord grape juice | Dietary Supplement | Several ounces Concord grape juice administered 3 times a day for 12 or 16 weeks. Specific dosage determined by participant's weight. |
|
| Measure | Description | Time Frame |
|---|---|---|
| memory performance | at the end of the intervention |
| Measure | Description | Time Frame |
|---|---|---|
| cortisol | at the end of the intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Robert Krikorian, Ph.D. | University of Cincinnati | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Cincinnati | Cincinnati | Ohio | 45267-0559 | United States |
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| placebo juice | Dietary Supplement | several ounces placebo juice consumed three times a day for 12 or 16 weeks; dosage determined according to participant's weight |
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| blueberry juice | Dietary Supplement | wild blueberry juice administered daily for 12 weeks, dosage determined according to participant's weight |
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| whole fruit blueberry powder | Dietary Supplement | whole fruit, freeze dried blueberry powder derived from a blend of cultivated blueberries administered daily for 16 weeks |
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| berry placebo powder | Dietary Supplement | berry placebo powder administered daily for 16 weeks |
|