Vibration Response Imaging in Chronic Obstructive Pulmonary Disease and Asthma

Evaluation of Vibration Response Imaging (VRI) in Chronic Obstructive Pulmonary Disease and Asthma Patients Before and After Bronchodilators

Obstructive lung disease is usually a differential diagnostic consideration when a patient presents with breathlessness or cough. Spirometry is the key diagnostic test used to confirm airflow obstruction particularly in the primary care setting. Airflow obstruction that completely resolves after administration of a bronchodilator, by definition, excludes a diagnosis of COPD. Evaluation of obstructive lung disease must include pulmonary function testing; bronchoreversibility testing is an adjunct in differentiating between asthma and COPD. Bronchoreversibility cannot serve as an absolute diagnostic criterion for separating asthma from COPD.

Vibration response imaging (VRI) technology provides a simple, radiation-free method to image the lungs, by visualizing vibration energy (lung sounds) emitted during respiration cycle. In this study, regional quantitative and qualitative information on vibration response is compared with spirometry in assessing lungs function of COPD and Asthma patients.

Inclusion Criteria:

• Able and willing to read, understand, and provide written Informed Consent
• Male or Female in the age range of 18-85 years
• Patients referred for evaluation of known or suspected obstructive airways disease.
• Subject is referred for pulmonary function testing with pre-and post- bronchodilator
• BMI > 21
• Patients who are treated with Bronchodilators should go through a washout period prior the VRI procedure according to the Pulmonary Function Laboratory protocol.
• Stable clinical condition at study baseline evaluation.

Exclusion Criteria:

• Chest wall deformation
• Spine deformation (including severe scoliosis)
• Hirsutism
• Potentially contagious skin lesion on the back
• Skin lesion that would interfere with sensor placement
• Pregnant or lactating females.