Effect of MK0524A on Flushing Caused by Niacin (0524A-056)

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Tolerability and Effect of MK0524A on Niacin-Induced Acute Flushing in Lipid Clinic Patients

The primary objective of the study is to assess the effects of MK0524A in reducing flushing associated with niacin.

Inclusion Criteria:

• Patient is male or female between 18 and 70 years of age
• Females of reproductive potential must agree to take acceptable contraceptive precautions for the duration of the study

Exclusion Criteria:

• Patient has a history of hypersensitivity to niacin or niacin-containing products
• Patient is currently experiencing menopausal hot flashes
• Patient consumes more than 2 alcoholic beverages per day
• Patient has poorly controlled Type 1 or Type 2 diabetes mellitus
• Patient engages in vigorous exercise or an aggressive diet regimen